beta(1) and beta(2)-adrenergic receptor polymorphisms and idiopathic ventricular arrhythmias


Ulucan C., Cetintas V. , Tetik A. , Eroglu Z., Kayikcioglu M. , CAN L. H. , ...More

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, vol.19, no.10, pp.1053-1058, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 10
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1540-8167.2008.01202.x
  • Title of Journal : JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
  • Page Numbers: pp.1053-1058
  • Keywords: ventricular tachycardia, genetics, tachycardia, arrhythmias, beta adrenergic receptors, OUTFLOW TRACT TACHYCARDIA, BETA(1)-ADRENERGIC RECEPTOR, DIAGNOSIS, ADRENOCEPTORS, MANAGEMENT, MECHANISM, MUTATION, DOMAIN, RISK, GENE

Abstract

Genetics and Idiopathic Ventricular Arrhythmias. Introduction: Idiopathic ventricular arrhythmias commonly refer to ventricular tachycardia (VT) and/or frequent/monomorphic premature ventricular contractions (PVC) in patients with structurally normal heart. Activation of sympathetic tone has been shown to play an important role in the provocation and maintenance of these arrhythmias. We investigated whether common single nucleotide polymorphisms in the beta(1) and beta(2)-adrenergic receptors are associated with idiopathic ventricular arrhythmias.