Pulmonary arterial hypertension and pregnancy


Terek D. , Kayikcioglu M. , Kultursay H., Ergenoglu M. , Yalaz M. , Musayev O., ...More

JOURNAL OF RESEARCH IN MEDICAL SCIENCES, vol.18, no.1, pp.73-76, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1111/j.1742-1241.2011.02711.x
  • Title of Journal : JOURNAL OF RESEARCH IN MEDICAL SCIENCES
  • Page Numbers: pp.73-76
  • Keywords: Iloprost, newborn, pregnancy, pulmonary hypertension, sildenafil, survival, therapy, THERAPY, DISEASE

Abstract

This is the case report of a pregnant woman who refused pregnancy termination when diagnosed with pulmonary arterial hypertension (PAH) functional class 2-3 at the 24th week of gestation and of her newborn. A pregnant woman with PAH functional class 2-3 was treated with inhaled prostacyclin analog ( iloprost), oral sildenafil, oxygen, and low molecular weight heparin. She delivered at 32nd week by Cesarean section. The infant required oxygen up to 36th week postconceptional age and had a short steroid treatment. The mother needed close cardiovascular monitorization, intensive oxygen and pulmonary vasodilator therapy for 2 months and was discharged with oxygen and oral iloprost treatment. A multidisciplinary approach together with pulmonary vasodilator therapy may be succesful in such a high-risk pregnant woman.