Two Rare Causes of Hepatitis: Fascioliasis and Brucellosis

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Onal U. , YAMAZHAN T. , PULLUKÇU H. , TAŞBAKAN M. , TAMSEL S. , Erdogan D. D. , ...Daha Fazla

VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, cilt.23, ss.76-79, 2017 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 23 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/vhd.0009
  • Sayfa Sayıları: ss.76-79


Brucellosis and fascioliasis are zoonoses which induce different type of cell-mediated immune responses and rarely cause hepatitis with together. Brucellosis induces T helper type 1 (Th1) immune response whereas Fasciola hepatica induces T helper type 2 (Th2) immune. It may be speculated that chronic fascioliasis can predispose to brucellosis by suppression of Th1 response against brucellosis. In this paper, we present a patient who was diagnosed with brucellosis as well as chronic fasciolasis on the basis of parasite that was seen incidentally during the abdomen ultrasonography. To our knowledge, this case is one of the few cases in the literature that showing the co-infection of the liver by both fascioliasis and brucellosis.