Effect Of G2706A and G1051A polymorphisms of the ABCA1 gene on the lipid, oxidative stress and homocystein levels in Turkish patients with polycystic ovary syndrome

KARADENİZ M., ERDOĞAN M. , AYHAN Z., YALÇIN M., OLUKMAN M. , ÇETİNKALP Ş. , ...More

LIPIDS IN HEALTH AND DISEASE, vol.10, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10
  • Publication Date: 2011
  • Doi Number: 10.1186/1476-511x-10-193
  • Title of Journal : LIPIDS IN HEALTH AND DISEASE

Abstract

Background: Obesity, insulin resistance and hyperandrogenism, crucial parameters of Polycystic ovary syndrome (PCOS) play significant pathophysiological roles in lipidemic aberrations associated within the syndrome. Parts of the metabolic syndrome (low HDL and insulin resistance) appeared to facilitate the association between PCOS and coronary artery disease, independently of obesity. ABCA1 gene polymorphism may be altered this components in PCOS patients.