Differentially displayed proteins as a tool for the development of type 2 diabetes

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Dincer A., Onal S., Timur S. , Zeytunluoglu A., DUMAN E., Zihnioglu F.

ANNALS OF CLINICAL BIOCHEMISTRY, vol.46, pp.306-310, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46
  • Publication Date: 2009
  • Doi Number: 10.1258/acb.2009.009034
  • Page Numbers: pp.306-310


Background: Type 2 diabetes is a complex disease that still requires a great deal of work to be carried out to understand the pathophysiology. Recently, researchers have focused on studying the organs and tissues known to be involved in the development of the type 2 phenotype using a proteomic approach. Little work has been reported on plasma of type 2 diabetics in whom the clinical status has been well characterized. In this study, changes in plasma proteins of type 2 diabetics were investigated by proteomic analysis in well-characterized individuals with type 2 diabetes (early and late stage) and control groups (with or without a family history of diabetes).