Differentially displayed proteins as a tool for the development of type 2 diabetes


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Dincer A., Onal S., Timur S. , Zeytunluoglu A., DUMAN E., Zihnioglu F.

ANNALS OF CLINICAL BIOCHEMISTRY, cilt.46, ss.306-310, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1258/acb.2009.009034
  • Dergi Adı: ANNALS OF CLINICAL BIOCHEMISTRY
  • Sayfa Sayıları: ss.306-310

Özet

Background: Type 2 diabetes is a complex disease that still requires a great deal of work to be carried out to understand the pathophysiology. Recently, researchers have focused on studying the organs and tissues known to be involved in the development of the type 2 phenotype using a proteomic approach. Little work has been reported on plasma of type 2 diabetics in whom the clinical status has been well characterized. In this study, changes in plasma proteins of type 2 diabetics were investigated by proteomic analysis in well-characterized individuals with type 2 diabetes (early and late stage) and control groups (with or without a family history of diabetes).