Characteristics of multisystem organ failure in neonates


AVANOGLU A. , Ergun O. , BAKIRTAS F., ERDENER A.

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, cilt.7, ss.263-266, 1997 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 7 Konu: 5
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1055/s-2008-1071167
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayıları: ss.263-266

Özet

The records of 45 neonatal deaths in a four year period were reviewed retrospectively. Sixteen patients (35.5%) developed multisystem organ failure (MSOF). The criteria for pulmonary, hepatic, renal, hematologic, cardiac and microvascular failures were established. The onset of the first organ involvement was calculated in days prior to death. The earliest organ involved was kidney (14.2 +/- 15.1) followed by microvascular (9.4 +/- 7.6), hematologic (8.4 +/- 10.1), liver (6.8 +/- 6.7), lung (6.3 +/- 6.6) and cardiac (6.0 +/- 8.7) failure. Blood culture analyses revealed 5 patients with culture-positive sepsis. Yeast was the leading septic agent (n = 3) followed by Klebsiella pneumoniae (n = 2), Pseudomonas sp. (n = 1) and E. coli (n = 1). The first organ involvement was noted at 17.6 +/- 23.2 days.