Oxidative stress biomarkers in four Bloom syndrome (BS) patients and in their parents suggest in vivo redox abnormalities in BS phenotype

ZATTERALE A., KELLY F. J. , DEGAN P., D'ISCHIA M., PALLARDO F. V. , CALZONE R., ...More

CLINICAL BIOCHEMISTRY, vol.40, no.15, pp.1100-1103, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 15
  • Publication Date: 2007
  • Doi Number: 10.1016/j.clinbiochem.2007.06.003
  • Title of Journal : CLINICAL BIOCHEMISTRY
  • Page Numbers: pp.1100-1103
  • Keywords: Bloom syndrome, oxidative stress, 8-hydroxy-2 '-deoxyguanosine, glutathione, uric acid, ascorbic acid, glyoxal, methylglyoxal, SISTER-CHROMATID EXCHANGES, PROOXIDANT STATE, FANCONI-ANEMIA, SUPEROXIDE-DISMUTASE, ACTIVE OXYGEN, DNA-DAMAGE, PROTEIN, WERNER, BLM, ACCUMULATION

Abstract

objective: To evaluate an association of Bloom syndrome (BS) phenotype with an in vivo prooxidant state.