Is resolution of vesicoureteric reflux by conservative management predictable in patients with myelodysplasia?

Ulman I. , Avanoglu A. , ERIKCI V., GOKDEMIR A.

EUROPEAN UROLOGY, vol.34, no.3, pp.226-229, 1998 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 1998
  • Doi Number: 10.1159/000019718
  • Title of Journal : EUROPEAN UROLOGY
  • Page Numbers: pp.226-229


Objective: To evaluate the probable factors that might predict the outcome of conservative management of vesicoureteric reflux (VUR) in myelodysplastic patients, Patients and Methods: A retrospective review of 24 children with VUR secondary to neurogenic bladder (l5 girls and 9 boys, age range 1-18 years) out of 75 myelodysplasia patients between 1994 and 1996 was made, Patients were grouped according to their response to conservative management: Group I: patients with their VUR resolved or downgraded (n = 15), and group II: patients with their VUR unchanged or increased (n = 9), The following parameters were compared between the two groups: age, sex, VUR grade and laterality, urodynamic parameters (bladder capacity, compliance, leak point pressure), type of bladder neuropathy, accompanying neuropathology (walking problem, anal incontinence), Results: Most of the parameters studied failed to predict the outcome of conservative management of VUR in patients with neurogenic bladder dysfunction, Higher grades of VUR if bilateral seem to benefit more from conservative management than lower grades do, Conservative management appears to be more effective in hyperreflexic bladders than areflexic bladders in terms of VUR resolution, Conclusion: Although prediction of patients resistant to conservative management of VUR could save myelodysplastic children from prolonged risk of renal damage, current methods of evaluation are of very little help in this aspect.