Alpha 2 integrin gene (ITGA2) polymorphism in renal transplant recipients with and without drug induced gingival overgrowth


GÜRKAN A. , EMİNGİL G. , AFACAN B., BERDELİ A. , Atilla G.

ARCHIVES OF ORAL BIOLOGY, cilt.59, ss.283-288, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Variances in fibroblasts' alpha 2 beta 1 integrin intensity may lead to altered adhesion to type I collagen and consequently to suppression of phagocytosis which may be one of the mechanisms for drug induced gingival overgrowth. The present study aimed to evaluate the genotype and allele frequencies of alpha 2 integrin +807 gene in renal transplant patients with and without gingival overgrowth.