Alpha 2 integrin gene (ITGA2) polymorphism in renal transplant recipients with and without drug induced gingival overgrowth


GÜRKAN A. , EMİNGİL G. , AFACAN B., BERDELİ A. , Atilla G.

ARCHIVES OF ORAL BIOLOGY, vol.59, no.3, pp.283-288, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1016/j.archoralbio.2013.12.003
  • Title of Journal : ARCHIVES OF ORAL BIOLOGY
  • Page Numbers: pp.283-288

Abstract

Background: Variances in fibroblasts' alpha 2 beta 1 integrin intensity may lead to altered adhesion to type I collagen and consequently to suppression of phagocytosis which may be one of the mechanisms for drug induced gingival overgrowth. The present study aimed to evaluate the genotype and allele frequencies of alpha 2 integrin +807 gene in renal transplant patients with and without gingival overgrowth.