Leukotriene receptor antagonism in experimental acute pancreatitis in rats


Oruc N. , Yukselen V., Ozutemiz A. Ö. , YUCE G., Celik H. , MUSOGLU A., ...More

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.16, no.4, pp.383-388, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1097/00042737-200404000-00003
  • Title of Journal : EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Page Numbers: pp.383-388

Abstract

Objectives Acute pancreatitis is a multifactorial disease caused by activation of several inflammatory mediators. Leukotrienes, beside other mediators, may be involved in acute pancreatitis. The aim of this study was to investigate the effects of 'zafirlukast', a leukotriene receptor antagonist, in acute pancreatitis and its relation with prostaglandin synthesis.