Nitric oxide and the endothelium: History and impact on cardiovascular disease


Yetik-Anacak G. , CATRAVAS J. D.

VASCULAR PHARMACOLOGY, cilt.45, ss.268-276, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 45 Konu: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.vph.2006.08.002
  • Dergi Adı: VASCULAR PHARMACOLOGY
  • Sayfa Sayısı: ss.268-276

Özet

There are few discoveries with the magnitude of the impact that NO has had on biology during the 25 years since its discovery. There is hardly a disease today not associated with altered NO homeostasis. In fact, despite numerous other endothelial functions, endothelial dysfunction has become synonymous with reduced biological activity of NO.