Stiff Person Syndrome-The Less Common Antibody: A Case Report


ÖZDEMİR H. N. , YÖNDEM D. , KAPLAN ÖZDEMİR S. , GÖKÇAY F.

TURKISH JOURNAL OF NEUROLOGY, cilt.26, ss.39-41, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 26 Konu: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/tnd.galenos.2019.80708
  • Dergi Adı: TURKISH JOURNAL OF NEUROLOGY
  • Sayfa Sayıları: ss.39-41

Özet

Stiff Person syndrome (SPS) is a rare, disabling syndrome characterized by progressive muscle stiffness and axial rigidity. It may have an autoimmune, paraneoplastic or cryptogenic etiology. A 59-year-old woman presented with stiffness and involuntary spasms in the lower extremities. In a neurologic examination, lower extremity and axial rigidity were revealed. Anti-glutamic acid decarboxylase antibody was negative, anti-amphiphysin was antibody positive. She was diagnosed as having SPS. The symptoms were improved after intravenous immunoglobulin and cancer therapy.