Comparison of tropisetron and granisetron in the control of nausea and vomiting in children receiving combined cancer chemotherapy


Aksoylar S. , AKMAN S. A. , OZGENC F., Kansoy S.

PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.18, ss.397-406, 2001 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 18 Konu: 6
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1080/088800101316922029
  • Dergi Adı: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Sayfa Sayıları: ss.397-406

Özet

Tropisetron and granisetron are selective serotonin (5-HT3) antagonists that have been proven effective in the prevention of nausea and vomiting in adults and children receiving cancer chemotherapy. This prospective, randomised study was designed to compare the efficacy of the two agents in the prevention of vomiting and nausea in children receiving highly emetogenic chemotherapy for various malignancies.