Scintigraphic imaging with a peptide glucuronide in rabbits: Tc-99m-exorphin C glucuronide


ERTAY T., Unak P. , Biber F. Z. , TAŞÇI C., Zihnioglu F. , DURAK H.

APPLIED RADIATION AND ISOTOPES, cilt.65, ss.170-175, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 65 Konu: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.apradiso.2006.03.017
  • Dergi Adı: APPLIED RADIATION AND ISOTOPES
  • Sayfa Sayısı: ss.170-175

Özet

A peptide glucuronide (Exorphin C glucuronide) was labeled with Tc-99m using glucoheptonate (GH) as a bifunctional chelating agent. Scintigraphic imaging was performed in male Albino rabbits. Exorphin C glucuronide showed rapid and efficient labeling with Tc-99m using glucoheptonate as a bifunctional chelate. Results demonstrated that Tc-99m-GEG may be a useful new type of glucuronide derivative of peptides for diagnosis of some cancer diseases. (c) 2006 Elsevier Ltd. All rights reserved.