This study investigated the differences between knitted fabrics made from compact and conventional ring-spun yarns. 100% cotton yarns produced from the same cotton blend, were spun according to compact and conventional ring spinning principles in two different yarn counts and twist factors. Three different knitting structures, i.e., interlock, rib and single jersey, were produced from these yarns. The physical properties of these fabrics were investigated and compared with each other before and after the reactive dyeing process. When the results were examined, it was found that the hairiness of compact yarns was less and the strength and elongation percentages were higher, less tendency to pilling and had a higher bursting strenght. No statistical differences were observed with regard to spirality, weight, abrasion resistance, color efficiency and rubbing fastness of the fabrics produced with compact and ring-spun yarns.