The Detrimental Effects of Diabetes on Pluripotency Determined by KLF4, SOX2, C-MYC and OCT4 Immunoreactivity in Rat Testes


AKTUĞ H. , UYSAL A. , YAVAŞOĞLU A. , OLTULU F. , AKARCA S. O. , YILMAZ-DILSIZ Ö. , ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.22, ss.327-335, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 22 Konu: 3
  • Basım Tarihi: 2013
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Sayfa Sayıları: ss.327-335

Özet

Background. Diabetes mellitus (DM) is a multisystem disorder. Type 1 DM can be experimentally induced in rats with streptozotocin (STZ). Diabetic conditions result in testicular oxidative stress and suppressed male reproductive activity as well as decreases in both testicular organ weights and subject weights.