Quercetin inhibits swarming motility and activates biofilm production of Proteus mirabilis possibly by interacting with central regulators, metabolic status or active pump proteins


AYGÜL A., Ozturk I., ÇİLLİ F. F. , ERMERTCAN Ş.

PHYTOMEDICINE, cilt.57, ss.65-71, 2019 (SCI İndekslerine Giren Dergi)

Özet

Background: Via its virulence factors such as swarm differentiation, biofilm and hemolysin production, urease enzyme, Proteus mirabilis causes urinary tract infections (UTIs), especially in complicated cases. Anti-pathogenic compounds attenuate the virulence of bacteria without showing 'cidal' activity and carry the potential to be used in the prevention and treatment of infectious diseases.