Effect of oxytocin administration on nerve recovery in the rat sciatic nerve damage model


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Gumus B., Kuyucu E., Erbas O. , Kazimoglu C., OLTULU F. , Bora O. A.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, cilt.10, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1186/s13018-015-0301-x
  • Dergi Adı: JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH

Özet

Background: Growth factors such as nerve growth factor (NGF) and insulin-like growth factor-1 (IGF-1) have been shown to play a role in the healing process of nerve injury. Recent researches have also shown that oxytocin administration activates these growth factors of importance for the healing of nerve tissue. The objective of the present study was to evaluate the effects of oxytocin on peripheral nerve regeneration in rats.