FGF-23 levels are associated with vascular calcification, but not with atherosclerosis, in hemodialysis patients

Turan, Mehmet; Kırcellı, Fatih; Yaprak, Mustafa; Sisman, Ali; Gungor, Ozkan; Bayraktaroğlu, SELEN; Özkahya, MEHMET; Aşcı, GÜLAY; Floege, Jurgen; Ok, ERCAN

doi:10.1007/s11255-016-1231-1

FGF-23 levels are associated with vascular calcification, but not with atherosclerosis, in hemodialysis patients

Turan M. N. , Kırcellı F., Yaprak M., Sisman A. R. , Gungor O., Bayraktaroğlu S. , ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.48, pp.609-617, 2016 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 48
Publication Date: 2016
Doi Number: 10.1007/s11255-016-1231-1
Title of Journal : INTERNATIONAL UROLOGY AND NEPHROLOGY
Page Numbers: pp.609-617
Keywords: Fibroblast growth factor-23, Coronary artery calcification, Carotid artery intima-media thickness, Hemodialysis, GROWTH-FACTOR 23, CHRONIC KIDNEY-DISEASE, CORONARY-ARTERY CALCIFICATION, LEFT-VENTRICULAR HYPERTROPHY, CARDIOVASCULAR-DISEASE, FACTOR-23 FGF-23, CAROTID-ARTERY, FIBROBLAST, BONE, PROGRESSION

Abstract

High fibroblast growth factor-23 (FGF-23) levels are associated with mortality and cardiovascular events in patients with chronic kidney disease. The aim of this cross-sectional study was to investigate the relationship between plasma FGF-23 levels and coronary artery calcification and carotid artery intima-media thickness (CA-IMT) in hemodialysis (HD) patients.