Oxidative stress markers in saliva and periodontal disease status: modulation during pregnancy and postpartum


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GÜMÜŞ P. , EMİNGİL G. , Ozturk V., Belibasakis G. N. , Bostanci N.

BMC INFECTIOUS DISEASES, vol.15, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15
  • Publication Date: 2015
  • Doi Number: 10.1186/s12879-015-1003-z
  • Title of Journal : BMC INFECTIOUS DISEASES
  • Keywords: Pregnancy, Saliva, Periodontal disease, Oxidative stress, Reactive oxygen species, GINGIVAL CREVICULAR FLUID, LOW-BIRTH-WEIGHT, TOTAL ANTIOXIDANT CAPACITY, GLUTATHIONE-PEROXIDASE, PROTEIN OXIDATION, REACTIVE OXYGEN, WHOLE SALIVA, IN-VIVO, SERUM, DNA

Abstract

Background: Periodontal diseases may affect local and systemic inflammation, and reactive oxygen species (ROS) levels. This systemic health burden could compromise the outcome of pregnancy in expectant mothers. The aim of the present study was to evaluate oxidative stress markers, including glutathione peroxidase (GPx), thiobarbituric acid-reactive substances (TBARS) and 8-hydroxy-2'-deoxyguanosine (8-OHdG), and total bacterial loads in the saliva of pregnant and postpartum women, and to investigate their association with periodontal disease severity.