Polycystic ovary syndrome is associated with increased osteopontin levels


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SAKLAMAZ A., ÇALAN M., YILMAZ O., Kume T., Temur M., YILDIZ N., ...Daha Fazla

EUROPEAN JOURNAL OF ENDOCRINOLOGY, cilt.174, ss.415-423, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 174 Konu: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1530/eje-15-1074
  • Dergi Adı: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Sayfa Sayıları: ss.415-423

Özet

Objective: Osteopontin (OPN) is a multi-functional secreted glycoprotein that plays a crucial role in glucose metabolism and inflammatory process. Growing evidence suggests that there is a link between OPN and ovarian function. However, no such link has yet been found for OPN in polycystic ovary syndrome (PCOS). Our aim was to ascertain whether circulating OPN levels are altered in women with PCOS and to determine whether OPN levels differ between the follicular phase and mid-cycle of the menstrual cycle in eumenorrheic women.