Altered Antigenic Profiling and Infectivity of Porphyromonas gingivalis in Smokers and Non-Smokers With Periodontitis

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Zeller I., Hutcherson J. A. , Lamont R. J. , Demuth D. R. , Gümüş P., Nizam N. , ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.85, ss.837-844, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 85
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1902/jop.2013.130336
  • Sayfa Sayıları: ss.837-844


Background: Cigarette smokers are more susceptible to periodontal diseases and are more likely to be infected with Porphyromonas gingivalis than non-smokers. Furthermore, smoking is known to alter the expression of P. gingivalis surface components and compromise immunoglobulin (Ig) G generation. The aim of this study is to evaluate whether the overall IgG response to P. gingivalis is suppressed in smokers in vivo and whether previously established in vitro tobacco-induced phenotypic P. gingivalis changes would be reflected in vivo.