Scintigraphic imaging with Tc-99m exorphin C in rabbits


ERTAY T., UNAK P. , TASCI C., Zihnioglu F. , DURAK H. İ.

APPLIED RADIATION AND ISOTOPES, cilt.62, ss.883-888, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 62 Konu: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.apradiso.2004.10.016
  • Dergi Adı: APPLIED RADIATION AND ISOTOPES
  • Sayfa Sayıları: ss.883-888

Özet

Exorphin C is a peptide with five amino acids [(Tyr-Pro-Ile-Ser-Leu) Trifluoroacetate salt] (Sigma) that has an affinity to opioid receptor-expressing tissues and tumors. Exorphin-C was labeled with Tc-99m using glucoheptonate (GH) as bifunctional chelating agent. Then, we investigated its radiopharmaccutical potential as opioid receptor-expressing tissue on rabbits.