A New Robust Nonlinear Control Algorithm for the Regulation of Blood Glucose in Diabetic Patients

Ozyetkin M. M. , Nath N., Tatlicioglu E. , Dawson D. M.

IEEE International Conference on Control Applications (CCA) Part of 6th IEEE Multi-Conference on Systems and Control (IEEE MSC), Dubrovnik, Croatia, 3 - 05 October 2012, pp.1057-1061 identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Volume:
  • Doi Number: 10.1109/cca.2012.6402670
  • City: Dubrovnik
  • Country: Croatia
  • Page Numbers: pp.1057-1061


Diabetes mellitus is a growing health problem worldwide. Especially, the patients with Type 1 diabetes need strict glycemic control because they have deficiency of insulin production. Today, the aim of the researchers is to develop a fully automated closed loop control system (i.e., artificial pancreas which is capable of continuous glucose sensing and regulating) that replicates the function of pancreatic beta cells. This equipment is supposed to be capable of maintaining normal blood glucose level on a desired level (4-6.2 mmol/L) and taking all factors affecting glucose concentration into account without inducing hypoglycemia and hyperglycemia.