Anti toxic effect of broccoli extract on stannous dichloride toxicity


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ÇEKİÇ B., MUFTULER F. Z. B. , Kilcar A. , GUNAY N., SAKARYA S., Unak P.

ACTA CIRURGICA BRASILEIRA, cilt.27, ss.606-610, 2012 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 27 Konu: 9
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1590/s0102-86502012000900003
  • Dergi Adı: ACTA CIRURGICA BRASILEIRA
  • Sayfa Sayısı: ss.606-610

Özet

PURPOSE: Since Technetium-99m (Tc-99m) has favorable physical and chemical characteristics, it is widely used radioisotope in Nuclear Medicine. However, stannous dichloride (SnCl2) has been widely used as a reducing agent in labeling procedure of pharmaceutical with radionuclide, it has been realized that SnCl2 have genotoxic and cytotoxic effects on biological systems. In previous studies, it has been shown that some herbal extract can reduce genotoxic and cytotoxic effects of SnCl2. In the present study, it is aimed to evaluate the effect of the broccoli extract on the survival of E. coli ATCC 25922 strain against to toxic effects of SnCl2.