Association between serum paraoxonase activity and oxidative stress in acute coronary syndromes


Kabaroglu C. , Mutaf I. , Boydak B. , OZMEN D., Habif S. , ERDENER D., ...More

ACTA CARDIOLOGICA, vol.59, no.6, pp.606-611, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.2143/ac.59.6.2005242
  • Title of Journal : ACTA CARDIOLOGICA
  • Page Numbers: pp.606-611

Abstract

Objective-The oxidation of low-density lipoprotein (LDL) is believed to have a central role in atherogenesis. Under oxidative stress not only LDL, but all other serum lipids are exposed to oxidation. High-density lipoprotein (HDL)-associated paraoxonase (PONI) was shown to inhibit LDL and HDL oxidation. We investigated the relationship between PONI and oxidative stress in acute myocardial infarction and unstable angina in a comparative fashion.