Development of a serum free medium for HUMIRA (R) biosimilar by design of experiment approaches


Kimiz-Gebologlu I., Saglam-Metiner P., Ozaslan O., AYYILDIZ TAMİŞ D. , Deliloglu-Gurhan S. I. , GÜLÇE İZ S.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, ss.283-294, 2020 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 45 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1515/tjb-2019-0268
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Sayfa Sayıları: ss.283-294

Özet

Background: Serum have been traditionally used to support growth of animal cell cultures. However, the increasing growth of therapeutic biopharmaceuticals market, accelerated the high demand for the serum-free medium (SFM).