A cross-sectional, mono-centric pilot study of insulin resistance in enzyme replacement therapy patients with Gaucher type I without overweight


Ucar S. K. , ÇOKER M. , ARGIN M. , Akman S., KARA s., Simsek D. G. , ...Daha Fazla

MOLECULAR GENETICS AND METABOLISM, cilt.96, ss.50-51, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 96 Konu: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.ymgme.2008.10.001
  • Dergi Adı: MOLECULAR GENETICS AND METABOLISM
  • Sayfa Sayıları: ss.50-51

Özet

Insulin resistance have been demonstrated in untreated patients with Gaucher type I disease. It was implied in overweight enzyme replacement therapy (ERT) treated patients with Gaucher type I disease. In present study we investigate whether insulin resistance is presented in fourteen ERT treated patients with Gaucher type I disease and without overweight in comparison to normal subjects. This work illustrates the presence of insulin resistance in non-overweight ERT treated patients with Gaucher type I disease. (C) 2008 Elsevier Inc. All rights reserved.