The Relationship between Melatonin and Cannabinoid-1 Receptor in Cortical Dysplasia Generated Rats

ERDOGAN E., UYANIKGİL Y. , OZTAS E.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.31, no.2, pp.346-354, 2014 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2014
  • Title of Journal : JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Page Numbers: pp.346-354

Abstract

Objectives: Cortical dysplasia is a developmental malformation that occurs as a result of defects in neuronal proliferation, migration and organization during the formation of brain cortex layers. Cannabinoid-1 Receptor (CB1R) plays a role in brain cortex development. Melatonin neuroprotective is an agent. In this study using an experimental cortical dysplasia model, CB1R expression and the effect of melatonin on CB1R were investigated.