The Relationship between Melatonin and Cannabinoid-1 Receptor in Cortical Dysplasia Generated Rats


ERDOGAN E., UYANIKGİL Y. , OZTAS E.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.31, ss.346-354, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 31 Konu: 2
  • Basım Tarihi: 2014
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Sayfa Sayıları: ss.346-354

Özet

Objectives: Cortical dysplasia is a developmental malformation that occurs as a result of defects in neuronal proliferation, migration and organization during the formation of brain cortex layers. Cannabinoid-1 Receptor (CB1R) plays a role in brain cortex development. Melatonin neuroprotective is an agent. In this study using an experimental cortical dysplasia model, CB1R expression and the effect of melatonin on CB1R were investigated.