TLR2 Arg753Gly, TLR4 Asp299Gly and Thr399lle gene polymorphisms are not associated with chronic periodontitis in a Turkish population


Berdeli A. , EMINGIL G. , SAYGAN B. H. , GUERKAN A., Atilla G. , KOESE T., ...More

JOURNAL OF CLINICAL PERIODONTOLOGY, vol.34, no.7, pp.551-557, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 7
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1600-051x.2007.01092.x
  • Title of Journal : JOURNAL OF CLINICAL PERIODONTOLOGY
  • Page Numbers: pp.551-557
  • Keywords: chronic periodontitis, gene polymorphisms, pathogenesis, periodontal disease, TLR, TOLL-LIKE RECEPTORS, INNATE IMMUNE-RESPONSE, SINGLE-NUCLEOTIDE POLYMORPHISMS, RISK-FACTORS, DISEASE, MUTATIONS, CD14, TOLL-LIKE-RECEPTOR-4, LIPOPOLYSACCHARIDE, IDENTIFICATION

Abstract

Aim: Toll-like receptor (TLR) gene polymorphisms could affect the host's ability to respond to microbial pathogens. In this case-control study, the association of TLR2 and TLR4 gene polymorphisms with chronic periodontitis (CP) was investigated.