The Metabolic Impacts of Nitric Oxide and its Metabolites: A Brief Review

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Oral O. , Tatlıbal P., Nomikos G., Nomikos N.

Biomedical Journal of Scientific & Technical Research, no.43, pp.34524-34526, 2022 (Refereed Journals of Other Institutions)

  • Publication Type: Article / Review
  • Publication Date: 2022
  • Title of Journal : Biomedical Journal of Scientific & Technical Research
  • Page Numbers: pp.34524-34526


Background: The study aims to investigate and evaluate the metabolic impacts of nitric oxide on body functions for healthy living.

Materials and Methods: In the search for scientific literatures related to this review the US National Library of Medicine (PubMed), MEDLINE and Sport Discus data and the terms “endothelium-derived relaxing factor (EDRF)”, “nitric oxide”, ‘’nitric oxide metabolites’’ and ‘’health ‘’were used.

Results: While almost all known free oxygen radicals are harmful at any concentration, nitric oxide (NO) plays a role in the regulation of many important physiological events such as blood pressure, sportive performance and immunological functions at low concentrations.

Conclusion: Nitrite Oxide (NO) is located in the guanidine group of the arginine amino acid, formed as a result of the reaction of nitrogen atom and molecular oxygen, and is a lipid and water-soluble free radical with many metabolic functions and also some pathophysiological mechanisms.