Reduced left uncinate fasciculus fractional anisotropy in deficit schizophrenia but not in non-deficit schizophrenia


KİTİŞ Ö. , ÖZALAY O., Zengin E. B. , HAZNEDAROĞLU D., Eker M. Ç. , YALVAÇ D., ...More

PSYCHIATRY AND CLINICAL NEUROSCIENCES, vol.66, no.1, pp.34-43, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1111/j.1440-1819.2011.02293.x
  • Title of Journal : PSYCHIATRY AND CLINICAL NEUROSCIENCES
  • Page Numbers: pp.34-43

Abstract

Aims: Schizophrenia is a psychiatric disorder manifesting with heterogeneous symptom clusters and clinical presentations. The deficit syndrome is the condition defined by the existence of primarily negative symptoms, and patients with the deficit syndrome differ from non-deficit patients on measures of brain structure and function. In the current study, by using diffusion tensor imaging (DTI), we investigated the frontotemporal connectivity that is hypothesized to differ between deficit and non-deficit schizophrenia.