A Convenient Synthesis of a Cardiac Sugar: "D-Digitalose"


KÖK G. , SALMAN Y. G.

JOURNAL OF CARBOHYDRATE CHEMISTRY, vol.31, pp.1-9, 2012 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31
  • Publication Date: 2012
  • Doi Number: 10.1080/07328303.2011.624285
  • Title of Journal : JOURNAL OF CARBOHYDRATE CHEMISTRY
  • Page Numbers: pp.1-9
  • Keywords: Cardiac sugar, Orthoester, Orthoester hydrolysis, D-Digitalose, D-Galactose, TRICHLOROETHYLIDENE ACETALS, GLYCOSIDE ACTIVITY, DIGITOXIN, CHARTREUSIN, ELSAMICIN, CANCER

Abstract

D-Digitalose (6-deoxy-3-O-methyl-D-galactose), a biologically important sugar that is found in some cardiac glycosides, was synthesized from D-galactose via 3-O-methyl-1,2,5-O-orthodichloroacetyl-alpha-D-galactofuranose.