Formulation and In Vitro Evaluation of Self Microemulsifying Drug Delivery System Containing Atorvastatin Calcium

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Atıf İçin Kopyala

Diril M., Turkyilmaz G. , KARASULU H. Y.

CURRENT DRUG DELIVERY, cilt.16, ss.768-779, 2019 (SCI İndekslerine Giren Dergi)

• Cilt numarası: 16 Konu: 8
• Basım Tarihi: 2019
• Doi Numarası: 10.2174/1567201816666190820143957
• Dergi Adı: CURRENT DRUG DELIVERY
• Sayfa Sayıları: ss.768-779

Özet

Objective: The aim of this study was to develop a new dosage form as an alternative to the classical tablet forms of atorvastatin calcium (AtrCa). The formulation strategy was to prepare an optimum self micro emulsifying drug delivery system (SMEDDS) to overcome the problem of low solubility of the active substance.