Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy


Erbas O., OLTULU F. , Yilmaz M., YAVAŞOĞLU A. , TAŞKIRAN D.

DIABETES RESEARCH AND CLINICAL PRACTICE, vol.114, pp.106-116, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 114
  • Publication Date: 2016
  • Doi Number: 10.1016/j.diabres.2015.12.016
  • Title of Journal : DIABETES RESEARCH AND CLINICAL PRACTICE
  • Page Numbers: pp.106-116

Abstract

Objective: Diabetic neuropathy (DNP) is a frequent and serious complication of diabetes mellitus (DM) that leads to progressive and length-dependent loss of peripheral nerve axons. The purpose of the present study is to assess the neuroprotective effects of levetiracetam (LEV) on DNP in a streptozotocin (STZ)-induced DM model in rats.