Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy


Erbas O., OLTULU F. , Yilmaz M., YAVAŞOĞLU A. , TAŞKIRAN D.

DIABETES RESEARCH AND CLINICAL PRACTICE, cilt.114, ss.106-116, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 114
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.diabres.2015.12.016
  • Dergi Adı: DIABETES RESEARCH AND CLINICAL PRACTICE
  • Sayfa Sayıları: ss.106-116

Özet

Objective: Diabetic neuropathy (DNP) is a frequent and serious complication of diabetes mellitus (DM) that leads to progressive and length-dependent loss of peripheral nerve axons. The purpose of the present study is to assess the neuroprotective effects of levetiracetam (LEV) on DNP in a streptozotocin (STZ)-induced DM model in rats.