Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey


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Turk M., KAPTAN F., TURKER N., KORKMAZ M. , EL S. N. , OZKAYA D., ...Daha Fazla

PARASITE-JOURNAL DE LA SOCIETE FRANCAISE DE PARASITOLOGIE, cilt.13, ss.65-70, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13 Konu: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1051/parasite/2006131065
  • Dergi Adı: PARASITE-JOURNAL DE LA SOCIETE FRANCAISE DE PARASITOLOGIE
  • Sayfa Sayıları: ss.65-70

Özet

Epidemiological, clinical and laboratory data were collected during an outbreak of trichinellosis, which occurred in Izmir, Turkey, between January and March 2004. The source of the infection was raw meatballs made with a mixture of uncooked beef and pork. Of 474 persons who were admitted at the Ataturk Training and Research Hospital during this period with a history of row meatball consumption, the diagnosis of Irichinellosis was confirmed for 154 (32.5 %, 87 males and 67 females; mean age 3 1 years, range 6-67 years). Among persons with a confirmed diagnosis, 79 % had myalgia, 77 % weakness and malaise, 63 % arthralgia, 40 % low pain, 68 % fever, 63 % periorbital and/or facial oedema, 49 % oedema at the trunk and limb, 42 % abdominal pain, 40 % nausea and vomiting, 28 % diarrhoea, 23 % subconjunctival haemorrhoge, 25 % macular or petechial rash, 4 % subungual haemorrhage, 15 % cardiac complaints and 0.2 % neurological complaints. Nine patients (5.8 %) were hospitalised due to severe myalgia (n = 2), high fever (n = 3), neurological manifestations (n = 1), thrombophlebitis (n = 2) and palmar erythema (n = 1). Eosinophilic was present in 88 % of the confirmed cases of the admission. Elevated levels of serum creatine phosphokinase, lactic dehydrogenase and aspartate aminotransferase were detected in 72 %, 70 % and 16 % of the confirmed cases, respectively. The seroconversion occurred in most of the infected people between the 4(th) and 6(th) weeks after the infection. All of the confirmed cases were treated with mebendazole. People with severe symptoms were treated also with prednisolone (60 mg/day for three days) and those with a moderately severe clinical pattern received a non-steroid anti-inflammatory drug (naproxen sodium, 550 mg/day). All confirmed cases recovered without any clinical sequela.