Aliaga Bay is located on Aegean coast of Turkey and many industrial facilities such as shipbreaking, shipyards, petroleum refineries, the paper mills were placed around it. The scientific literature search has revealed that the chemical pollution of industrial origin is affecting the marine biota and human population directly or indirectly. Since many carcinogenic and mutagenic chemicals have been accumulated in aquatic sediments it is of great importance to search and monitor their genotoxic potential considering the contamination of aquatic organisms and human beings. In the present study it has been aimed to detect the mutagenic effects of the sediments from 6 stations on Aliaga Bay using AMES's test with TA98 and TA 100 strains of Salmonella typhimurium. According to the results, samples from the stations close to the shipbreaking shipyard were toxic and only the samples from St.3 and St.4 had values close to those for weak mutagenicity. As conclusion, Aliaga Bay is under influence of toxic and genotoxic pollution originating mainly from the shipbreaking and shipyards activities, wastewater of Aliaga Municipality and Aliaga Organized Industrial Zone and it is likely to experience greater environmental problems unless measures are taken to prevent it.