The Association Between The Extended Psychosis Phenotype and COMT val158met and BDNF val66met Polymorphisms


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Binbay T., Kırlı U., Mısır E., Elbi H. , Kayahan B., Onay H., ...More

TURK PSIKIYATRI DERGISI, vol.29, 2018 (Journal Indexed in SSCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29
  • Publication Date: 2018
  • Doi Number: 10.5080/u19426
  • Title of Journal : TURK PSIKIYATRI DERGISI

Abstract

Objective: Psychotic disorders were previously associated with catechol-O-methyltransferase (COMT) val(158)met (rs4680) and brain-derived neurotrophic factor (BDNF) val(66) met (rs6265) polymorphisms. This article evaluates the association between COMT/BDNF polymorphisms and the extended psychosis phenotype which covers not only schizophrenia but also subclinical expressions of psychotic experiences.