Exploring comparative effects of sodium lauryl sulphate (SLS) and sodium laureth sulphate (SLES) zebrafish embryos and larvae

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Gökçe B., Kıran M., İşisağ Üçüncü S.

International Eurasian Conference on Biological and Chemical Sciences, Ankara, Türkiye, 28 Haziran 2019

  • Basıldığı Şehir: Ankara
  • Basıldığı Ülke: Türkiye



Currently, surfactants are widely distributed in the environments and have been continuously detected within aquatic environments as a consequence of their use on a global scale. As organic pollutants, their effects have drawn extensive attention. Sodium Lauryl Sulphate also is known as Sodium Dodecyl Sulphate (SLS / SDS) is a synthetic organic compound and used as an anionic surfactant in many hygiene products. Sodium Laureth Sulfate or Sodium Lauryl Ether Sulfate (SLES) is an anionic detergent and used as a foaming agent in many personal care products. SLES is produced from SLS with the ethoxylation process. In this study, the effects of SLS and SLES surfactants on zebrafish larval behavior were explored and compared. Five behavioral parameters were recorded using larval rest/wake assay including rest total, the number of rest bouts, rest bouts length, total activity, and waking activity. Moreover, we also tested the toxicities of these surfactants in developing zebrafish embryos. Results were indicated that these surfactants have concentration-dependent effects on zebrafish larval behavior and embryonic development. Our findings provide references for ecotoxicological comparison of different types of surfactants and first comparative results for SLES toxicity.

Keywords: Sodium Lauryl Sulphate, Sodium Dodecyl Sulphate, Sodium Laureth Sulfate, Zebrafish, Toxicity.