The paper investigates the patterns of technology and knowledge of the regions. The first aim of the paper is to determine cluster templates at the national level. The second aim of the paper is to investigate the technology and knowledge composition of the regional highpoint clusters. The paper identifies patterns of industrial linkages to define cluster templates and regional highpoints. The second part uncovers regional distributions of technology and knowledge. The data comes from Turkey's 2012 input-output table. The location quotients use industrial employment statistics from the Turkish Statistical Institute. The technological and knowledge intensity classification follows Eurostat. The findings reveal 10 cluster templates in Turkey. Spatial distribution of the highpoint clusters reveals that most regions contain highpoint clusters with low technology and low knowledge-intensive sectors. The results reveal that highpoint clusters in Turkey's regions contain industries whose technologies do not demand high skills, knowledge and sophistication. Limited existence of high-tech industries and low knowledge intensity in Turkey's industry composition is a limiting factor for transition to high value-added manufacturing. Special emphasis should be directed towards constructing regional advantage, given the current levels of technology and knowledge intensity.