Retrospective analysis of hysteroscopic findings in breast cancer patients having adjuvant tamoxifen treatment


Sendag F. , Sahin Ç. , Zeybek B., Terek M. C. , Oztekin K., Bilgin O.

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, cilt.31, ss.415-417, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 4
  • Basım Tarihi: 2010
  • Dergi Adı: EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
  • Sayfa Sayıları: ss.415-417

Özet

Purpose of Investigation: To evaluate the effects of tamoxifen on the endometrium of breast cancer patients by hysteroscopy and endometrial sampling. Methods: Thirty-seven breast cancer patients using tamoxifen underwent hysteroscopy because of postmenopausal endometrial thickening or abnormal uterine bleeding. Hysteroscopic findings were compared with histopathology and ultrasonographic measurement of the endometrium. Results: Nineteen women showed endometrial abnormalities (51%) out of 37 patients. Negative and positive predictive values for hysteroscopy in detecting endometrial abnormalities were 100% and 94%, respectively. Conclusion: Endometrial surveillance is an important part of gynecological follow-up in breast cancer patients using tamoxifen and the liberal use of hysteroscopy aids in the diagnosis of abnormal endometrium.