Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia


Avcu G., Karapinar D. Y. , Akinci A. B. , Sivis Z. O. , Sahin A., Bal Z. , ...More

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, vol.54, pp.8-12, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54
  • Publication Date: 2017
  • Doi Number: 10.1016/j.ijid.2016.10.027
  • Title of Journal : INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
  • Page Numbers: pp.8-12

Abstract

Objectives: Invasive aspergillosis (IA) is an important cause of mortality and morbidity in children with hematological malignancies. The monitoring of serum galactomannan (GM) antigen is considered useful in the diagnosis of IA. The aim of this study was to determine the utility of serum GM monitoring in the early diagnosis of IA and the role of positive antigenemia in the management of children with acute lymphoblastic leukemia (ALL).