Evaluation of GCF MMP-1, MMP-8, TGF-beta 1, PDGF-AB, and VEGF levels in periodontally healthy smokers


Eren G. , Turkoglu H. O. , Atmaca H., Atilla F. G.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, ss.850-856, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 45
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1405-112
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.850-856

Özet

Background/aim: The effect of smoking on inflammatory biomarkers in gingival crevicular fluid (GCF) is well established in the presence of periodontal inflammation. However, it is not clear if smoking has an influence on matrix metalloproteinase (MMP) and growth factor levels in the GCF of periodontally healthy subjects. The aim of this study was to investigate GCF levels of MMP-1, MMP-8, transforming growth factor (TGF)-beta 1, platelet-derived growth factor (PDGF)-AB, and vascular endothelial growth factor (VEGF) in smoking versus nonsmoking periodontally healthy subjects.