Effects of Silk Sericin on Incision Wound Healing in a Dorsal Skin Flap Wound Healing Rat Model


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ERSEL M. , UYANIKGİL Y. , Akarca F. , ÖZÇETE E. , ALTUNCI Y. A. , KARABEY F., ...More

MEDICAL SCIENCE MONITOR, vol.22, pp.1064-1078, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22
  • Publication Date: 2016
  • Doi Number: 10.12659/msm.897981
  • Title of Journal : MEDICAL SCIENCE MONITOR
  • Page Numbers: pp.1064-1078
  • Keywords: Antioxidants, Sericins, Wound Healing, REDUCING OXIDATIVE STRESS, NITRIC-OXIDE, LIPID-PEROXIDATION, PROTEIN SERICIN, GROWTH-FACTOR, BOMBYX-MORI, WASTE-WATER, IN-VITRO, REPAIR, TYROSINASE

Abstract

Background: The wound healing process is complex and still poorly understood. Sericin is a silk protein synthesized by silk worms (Bombyx mori). The objective of this study was to evaluate in vivo wound healing effects of a sericin-containing gel formulation in an incision wound model in rats.