Effect of prolonged administration of bovine lactoferrin in neuropathic pain: Involvement of opioid receptors, nitric oxide and TNF-alpha


Onal A., Kayalıoglu G. , Parlar A., Keser A. , Ulker S.

LIFE SCIENCES, cilt.86, ss.251-259, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 86
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.lfs.2009.12.007
  • Dergi Adı: LIFE SCIENCES
  • Sayfa Sayıları: ss.251-259

Özet

Aims: This study aimed to investigate the effect of prolonged administration of bovine milk lactoferrin (bLF) on hyperalgesia and allodynia in a rat model of neuropathic pain and to determine the involvement of c-Fos, TNF-alpha, nitric oxide and opioidergic systems in this effect.