This study was planned as a descriptive evaluation of School of Health students knowledge and healthy lifestyle behavior related to prevention of cancer. The study has been carried out in Nursing, Midwifery and Health Official Departments at Celal Bayar University School of Health, between November 2007 and January 2008. The subjects comprised 345 volunteer students. The data were collected using a questionnaire covering nutritional status and attitudes related to the prevention from cancer, and results were assessed using the Health Promotion Lifestyle Profile Scale. The mean age was 20.9 +/- 2.01 years and 22.6% were male. Some 88.4% of the students considered cancer to be a preventable illness and 70.1% of them believed that it could be preventedby healthy nutrition. The mean score of the Health Promotion Lifestyle Profile Scale was 124.8 ( SD, 19.9). In conclusion, it was found that students participating in this study have good level of knowledge on cancer prevention. Health behavior was found to be moderate.