Successful liver transplantation for giant cell hepatitis and Coombs-positive hemolytic anemia: A case report

Akyildiz M., Karasu Z. , Arikan C., Nart D., Kilic M.

PEDIATRIC TRANSPLANTATION, vol.9, no.5, pp.630-633, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 5
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1399-3046.2005.00346.x
  • Page Numbers: pp.630-633


Giant cell hepatitis (GCH) with autoimmune hemolytic anemia (AHA) is a distinct entity with an aggressive course. Drugs, autoimmunity, and viruses have been implicated in its etiology. Without treatment, liver dysfunction is progressive and fatal. Although succesful immunosuppressive treatment has been reported, a few patients have undergone liver transplantation with recurrence of the primary disease in the allograft. We report, an 18-year-old boy with progressive GCH with AHA without recurrence in the allograft following deceased donor (DD) liver transplantation.