Molecular Evaluation of t(14;18)(bcl-2/IgH) Translocation in Follicular Lymphoma at Diagnosis Using Paraffin-Embedded Tissue Sections


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Selvi N., Kosova B. , Hekimgil M. , Gunduz C. , KAYMAZ B. T. , Karaca E., ...More

TURKISH JOURNAL OF HEMATOLOGY, vol.29, no.2, pp.126-134, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.5505/tjh.2012.93898
  • Title of Journal : TURKISH JOURNAL OF HEMATOLOGY
  • Page Numbers: pp.126-134

Abstract

Objective: Follicular lymphoma (FL) is one of the most common lymphomas, and is characterized by t(14;18) (q32;q21) in more than 80% of patients. The aim of this study was to determine the rate of t(14;18) positivity based on the detection of mbr or mcr in paraffin-embedded tissue samples.