Molecular Evaluation of t(14;18)(bcl-2/IgH) Translocation in Follicular Lymphoma at Diagnosis Using Paraffin-Embedded Tissue Sections


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Selvi N., Kosova B. , Hekimgil M. , Gunduz C. , KAYMAZ B. T. , Karaca E., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.29, ss.126-134, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5505/tjh.2012.93898
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Sayfa Sayıları: ss.126-134

Özet

Objective: Follicular lymphoma (FL) is one of the most common lymphomas, and is characterized by t(14;18) (q32;q21) in more than 80% of patients. The aim of this study was to determine the rate of t(14;18) positivity based on the detection of mbr or mcr in paraffin-embedded tissue samples.