Benefits of statin treatment in cardiac syndrome-X

Creative Commons License

Kayikcioglu M. , Payzin S., Yavuzgil O., Kultursay H., Can L. H. , Soydan I.

EUROPEAN HEART JOURNAL, vol.24, no.22, pp.1999-2005, 2003 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 22
  • Publication Date: 2003
  • Doi Number: 10.1016/s0195-668x(03)00478-0
  • Title of Journal : EUROPEAN HEART JOURNAL
  • Page Numbers: pp.1999-2005


Aims The pathophysiological mechanism in cardiac syndrome-X (anginal chest pain, positive exercise test, and angiographically normal coronary arteries) has been suggested as an impairment in normal endothelial function of the coronary microvasculature, resulting in inadequate flow reserve. The aim of this study was to determine whether statins with proven beneficial effects on endothelium, have any effect on endothelial functions and exercise induced ischaemia in cardiac syndrome-X.