Fc gamma RIIa, IIIa and IIIb gene polymorphisms in Behcet's disease: do they have any clinical implications?


AKSU K. , KITAPCIOGLU G. , KESER G. , BERDELİ A. , KARABULUT G. , KOBAK S., ...Daha Fazla

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.26, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 26 Konu: 4
  • Basım Tarihi: 2008
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Özet

Objective. Behcets disease (BD) is a unique systemic vasculitis involving both arteries and veins of all sizes. Since Fc gamma receptors (Fc gamma R) are important in mediating various immune effector functions, Fc gamma R gene polymorphisms may affect the susceptibility to systemic inflammatory diseases such as BD. The aim of this study was to show the distribution of Fc gamma RIIa, IIIa ve IIIb receptor gene polymorphisms in BD, and to investigate possible genotype-phenotype relationships.